Triclosan

Description

~TRICLOSAN
English name: Triclosan 2,4,4 \'-trichloro-2\' -hydroxydiphenylether
Chemical name: 2, 4, 4\' -- trichloro-2 \'-- hydroxyl diphenyl ether, 5-chloro-2 - (2\', 4\' -dichlorophenoxy) phenol
Molecular formula: C12H7Cl3O2
Molecular weight: 289.5
CAS no. : 3380-34-5
EINECS No. 222-182-2
Appearance: white crystalline powder, slightly aromatic or phenolic.
Character:
1. Good compatibility -- it has strong compatibility with other components of the product formula, and can play a synergistic role without chemical reaction.
2. Strong solubility -- soluble in various organic solvents and water-soluble surfactants.
3, good stability -- in strong acid, strong base, high temperature environment with a high degree of stability. Ph value in the range of 1-12 has a strong antibacterial effect; It does not decompose rapidly below 280 -290℃
4. Low volatility -- the vapor pressure is 4x10-4 mmHg at 20℃ and 2x10-2 mmHg at 100℃.
5. Good safety -- no acute toxicity or chronic toxicity, no allergy or phototoxicity, no harm to the nervous system, no irritation to the skin, no accumulation on organs and carcinogenesis.
Function :
Triclosan is a highly effective broad-spectrum antibacterial agent, which has a wide range of killing and inhibiting effects on infections or pathogenic gram-positive bacteria and negative bacteria, fungi, yeast and viruses, as well as antibiotic resistant bacteria and non-antibiotic resistant bacteria.
It has strong antibacterial, anti-inflammatory and antipruritic effects.
Specication:
item specification Test result
Appearance White Crystalline powder conform
Odor Weak phenolic odor conform
Melting point 55.5- -57.5℃ 56.5 ℃
Solubility  Almost insoluble in water, soluble in methanol, alcohol and acetone, slightly soluble in n-hexane conform

Identify A. The infrared spectrum is consistent with the standard ref.
B. Chromatographic retention time is consistent with standard ref conform
water ≤0.1% 0.09% w/w
ash ≤ 0.1% 0.018% w/w
Heavy metals  0.002% ＜0.002%
impurity 0.5% 0.17%
4-Chlorophenol ≤50 mg/kg ＜ 50 mg/kg
2,4-Dichlorophenol ≤10 mg/kg ＜ 10 mg/kg
2,8-Dichlorodibenzo-p-Dioxin ≤ 0.25 mg/kg ＜ 0.25 mg/kg
2,4,8-Trichlorodibenzofuran ≤ 0.50 mg/kg ＜ 0.50 mg/kg
1,3,7-Trichlorodibenzo-p-Dioxin ≤ 0.25 mg/kg ＜ 0.25 mg/kg
2,8-Dichlorodibenzofuran ≤ 0.50 mg/kg ＜ 0.50 mg/kg
2,3,7,8-Tetrachloro Dibenzo-p-Dioxin ＜ 0.001ug/kg ＜ 0.001ug/kg
2,3,7,8-Tetrachloro Dibenzofuran ＜ 0.001ug/kg ＜ 0.001ug/kg
Assay(C12 H7 Cl3 O2) 97.0% - 103.0% (dry basis) 99.91%
Application:
1. Oral hygiene products
2. Cosmetics (facial cleansing products, hair and body cleaning products, special skin care products, body odor care products)
3. Health antibacterial soap categories
4. All kinds of adult care products
5. Antibacterial detergent
6. Dishwashing detergent
7. Medical equipment disinfectant
8. Antibacterial fabric finishing agent
9. Antibacterial polymer products
Storage: Keep containers tightly closed in a cool, well-ventilated place
Packing: 25 kg/cardboard barrels, lined with double polyethylene bag ( 38 * 50 cm).